Gene description for PTGIS
Gene name prostaglandin I2 synthase
Gene symbol PTGIS
Other names/aliases CYP8
CYP8A1
PGIS
PTGI
Species Homo sapiens
 Experiment description of studies that identified PTGIS in Smooth muscle cells

1
Experiment ID1351
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 32938681   
OrganismHomo sapiens
Experiment descriptionAnnexin A1-dependent tethering promotes extracellular vesicle aggregation revealed with single-extracellular vesicle analysis
AuthorsRogers MA, Buffolo F, Schlotter F, Atkins SK, Lee LH, Halu A, Blaser MC, Tsolaki E, Higashi H, Luther K, Daaboul G, Bouten CVC, Body SC, Singh SA, Bertazzo S, Libby P, Aikawa M, Aikawa E.
Journal name Sci Adv
Publication year2020
SampleSmooth muscle cells
Sample nameCarotid artery-derived primary smooth muscle cells
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
Western blotting
EV-TRACK -

2
Experiment ID1352
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry
PubMed ID 32938681   
OrganismHomo sapiens
Experiment descriptionAnnexin A1-dependent tethering promotes extracellular vesicle aggregation revealed with single-extracellular vesicle analysis
AuthorsRogers MA, Buffolo F, Schlotter F, Atkins SK, Lee LH, Halu A, Blaser MC, Tsolaki E, Higashi H, Luther K, Daaboul G, Bouten CVC, Body SC, Singh SA, Bertazzo S, Libby P, Aikawa M, Aikawa E.
Journal name Sci Adv
Publication year2020
SampleSmooth muscle cells
Sample nameCarotid artery-derived primary smooth muscle cells
Isolation/purification methodsDifferential centrifugation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry
EV-TRACK -

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